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there s a protein in our cells called PARP-1 that is constantly repairing damaged DNA our cells. But it can t repair the DNA in neurons (including brains) while we re awake. So it accumulates there until we fall asleep. Research now shows this accumulation of PARP-1 is what makes us sleepy.

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Fun Fact: there’s a protein in our cells called PARP-1 that is constantly repairing damaged DNA our cells. But it can’t repair the DNA in neurons (including brains) while we’re awake. So it accumulates there until we fall asleep. Research now shows this accumulation of PARP-1 is what makes us sleepy.

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researchgate.net

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